范瑞芳（华南师范大学生命科学学院教授）

人物经历

1991年本科毕业于河南师范大学

2000年硕士毕业于北京理工大学

2007年从中科院广州地球化学所博士毕业

主要成就

课题研究

[1] 国家自然科学基金（21777048），2018.01-2021.12，64万元，主持，在研。

[2] 国家自然科学基金重点项目（41731279），2018.01-2022.12，60/323万元，子课题负责人，在研。

[3] 国家自然科学基金 (21477041)，2015.01-2018.12, 87万元，主持，已结题。

[4] 广州市科技计划项目 (201510010107)， 2015.06-2018.06，20万，主持，已结题。

发表论文

(1) Jianhua Tan#, Hongxuan Kuang#, Xuejing Lv, Yingwei Zeng, Wenji Zhou, Qilai Xie *, Ruifang Fan*. Distribution characteristics and health risk assessment of a novel antibacterial alternative in personal care products: chloroxylenol. Science of the Total Environment, 2021, 786, 147524. （IF2019=6.551, 一区）

(2) Hongxuan Kuang, Zhilin Li, Xuejing Lv, Peiqiong Wu, Jianhua Tan, Qiurong Wu, Wenhui Jiang, Qihua Pang, Ruifang Fan*. Exposure to volatile organic compounds may be associated with oxidative DNA damage-mediated childhood asthma. Ecotoxicology and Environmental Safety, 2021, 210: 111864. (IF2019=4.872)

(3) Congcong Wang, Jiaying He, Tongfei Xu, Hongyu Han, Zhimin Zhu, Lingxue Meng, Qihua Pang*, Ruifang Fan*. Bisphenol A(BPA), BPS and BPB-induced oxidative stress and apoptosis mediated by mitochondria in human neuroblastoma cell lines, Ecotoxicology and Environmental Safety, 2021, 207:111299. (IF2019=4.872)

(4) Lingxue Meng, Jian Liu, Congcong Wang, Zedong Ouyang, Jiahua Kuang, Qihua Pang*, Ruifang Fan*. Sex specific neurotoxic effects of BPA and its analogs on primary hippocampal neurons attenuated by EGCG, Chemosphere, 2021, 264, 128450. (IF2019=5.778)

(5) Hongxuan Kuang, Jian Liu, Yingwei Zeng, Wenji Zhou, Peiqiong Wu, Jianhua Tan, Yonghong Li, Qihua Pang, Wenhui Jiang*, Ruifang Fan*. Co-exposure to polycyclic aromatic hydrocarbons, benzene and toluene may impair lung function by increasing oxidative damage and airway inflammation in asthmatic children. Environmental Pollution, 2020, 266,115220. (IF2019=6.792,一区)

(6) Yonghong Li, XueJing Lv, Jian Liu, Jianying He, Lingxue Meng, Hongxuan Kuang, Caihui Cha, Qihua Pang*, Ruifang Fan*, Association between 10 urinary heavy metals exposure and attention deficit hyperactivity disorder for children, Environmental Science and Pollution Research, 2020, 27:31233–31242. （SCI, IF2019=3.056）

(7) Haibin Zhang, Zhouyu Wang, Lingxue Meng, Hongxuan Kuang, Jian Liu, Xuejing Lv, Qihua Pang, Ruifang Fan*, Maternal exposure to environmental bisphenol A impairs the neurons in hippocampus across generations, Toxicology, 2020, 432:152393. (IF2019=4.099)

(8) Hongxuan Kuang, Yanyan Dai, Yonghong Li, Caihui Cha, Wenhui Jiang, Qihua Pang, Haibin Zhang, Ruifang Fan*. The association among blood BPDE-DNA adducts, serum interleukin-8 (IL-8) and overall DNA damage for children with pulmonary disease. International Journal of Environmental Health Research, 2019, 1-12. (SCI, IF2018=1.465)

(9) Hongxuan Kuang, Yonghong Li, Wenhui Jiang, Peiqiong Wu, Jianhua Tan, Haibin Zhang, Qihua Pang, Ruifang Fan*. Simultaneous determination of urinary 31 VOC metabolites，8-hydroxy-2′-deoxyguanosine and trans-3′-hydroxy-cotinine by UPLC-MS/MS: The effect of isotoped internal standards on elimination of matrix effect, Analytical and Bioanalytical Chemistry, 2019, 411:7841-7855. (SCI, IF2018=3.286)

(10) Haibing Zhang, Kuanghong Xuan, Yifan Luo, Shuhua Liu, Lingxue Meng, Qihua Pang, Ruifang Fan*. Low-dose bisphenol A exposure impairs learning and memory ability with alterations of neuromorphology and neurotransmitters in rats, Science of the Total Environment, 2019, 697:134036. （SCI, IF2018=5.589，一区）

(11) Qihua Pang#, Yanru Li#, Lingxue Meng, Guanyong Li, Zhiwei Luo, Ruifang Fan*. Neurotoxicity of BPA, BPS and BPB for the hippocampal cell line (HT-22): an implication for the replace of BPA in plastics，Chemosphere, 2019, 226:545-552. (SCI, IF2018=5.108, 2区)

(12) Laiguo Chen, Guocheng Hu, Ruifang Fan*, Yanshan Lv, Yanyan Dai, Zhencheng Xu*. Association of PAHs and BTEX exposure with lung function and respiratory symptoms among non-occupational population near the coal-chemical industry in Northern China. Environment International, 2018, 120:480-488. (SCI, IF2018=7.943, 1区)

(13) Yanru Li, Haibin Zhang, Hongxuan Kuang, Ruifang Fan*, Caihui Cha*, Guanyong Li, Zhiwei Luo, Qihua Pang. Relationship between Bisphenol A exposure and Attention-deficit/ hyperactivity disorder: A case-control study for primary school children in Guangzhou, China. Environmental Pollution, 2018, 235:141-149. (SCI, IF2018=5.714)

(14) Yuanxiu Zhou, Zhouyu Wang, Minghan Xia, Siyi Zhuang, Xiaobing Gong*, Jianwen Pan, Chuhua Li, Ruifang Fan*, Qihuang Pang, Shaoyou Lu. Neurotoxicity of low bisphenol A (BPA) exposure for young male mice: An implication for children exposed to environmental level of BPA, Environmental Pollution, 2017, 229:40-48. (SCI, IF2017=4.358)

(15) Yanshan Lv#, Shaoyou Lu#, Yanyan Dai, Caiyan Rui, Yongjun Wang, Yanru Li, Yuanxiu Zhou, Qihua Pang, Ruifang Fan*. Higher dermal exposure of cashiers to BPA and its association with DNA oxidative damage, Environment International, 2017, 98:69-74. (SCI, IF2017=7.297, 1区).

(16) Yanshan Lv, Caiyan Rui, Yanyan Dai, Qihua Pang, Yanru Li, Ruifang Fan*, Shaoyou Lu*. Children exposure to BPA through dust and the association of urinary BPA, triclosan with oxidative stress in Guangzhou, China. Environmental Science: processes & impact, 2016, 18: 1492-1499. (SCI, IF2016=2.592)

(17) Shaoyou Lu, Lu Ren, Jianzhang Fang, Jiajia Ji, Guihua Liu, Jianqing Zhang, Huimin Zhang, Ruorong Luo, Kai Lin, Ruifang Fan*. Trace elements can increase urinary 8-hydroxy-2’-deoxyguanosine level: a case study of college students in Guangzhou, China. Environmental Science and Pollution Research, 2016, 23:8484–8491. (SCI, IF2016=2.741)

社会任职

广东省环境科学学会生态毒理学与环境毒理学分会委员，广东省环境诱变剂协会理事，国家自然科学基金、科技部、教育部以及广东省等国家和省级项目评审专家，长期担任Environment International, Environmental Science & Technology, Toxicology等国际知名杂志的审稿人。

获奖情况

获得华南师范大学 “科研工作优秀奖”“优秀教师”“优秀班主任”等荣誉，培养的多名研究生获得“国家奖学金”、“广东省优秀学生（研究生）”以及校级“优秀硕士论文”等奖励和荣誉称号；2019年指导本科生获得“第15届《挑战杯》广东大学生课外学术科技作品竞赛二等奖”。

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